Fas Pulls the Trigger on Psoriasis

Plant Signaling: Ubiquitin Pulls the Trigger on Chloroplast Degradation

Diverse proteolytic pathways regulate chloroplasts. Recent work has revealed significant new roles for chloroplast ubiquitination in stress adaptation, involving targeted protein removal through the ubiquitin-proteasome system, or selective, whole-chloroplast degradation.

Reflections on a sticky situation: how surface contact pulls the trigger for bacterial adhesion.

Adhesion of bacterial cells to surfaces can be mediated by a wide variety of extracellular structures, which can either recognize specific molecular motifs or adhere in non-specific ways to multiple types of surfaces. The attachment is thought to be highly regulated, but the underlying sensory mechanism(s) are poorly understood. In the α-proteobacterium Caulobacter crescentus, the formation of ...

What Pulls the Trigger of Reflection? — Conflict Awareness and Adaptive Scaffolding —

Trigger factors in childhood psoriasis and vitiligo.

Psoriasis and vitiligo are very common skin disorders that may have a profound impact upon the affected individuals; the etiology of both diseases includes genetic factors and triggers, which could be endogenous or exogenous. Two groups of children population consisting of 153 patients suffering from skin disorder (65 with vitiligo and 88 with psoriasis) have been examined at the Department of ...

Mdm2 pulls the plug on glycolysis

C ancer cells have long been known to have higher rates of glycolysis than normal cells, a phenomenon named the Warburg effect after its discoverer Otto Warburg (1). Enhanced glycolysis is thought to allow cancer cells to survive the hypoxic conditions they experience in the center of solid tumors. But Mikawa et al. reveal how damaged cells switch off glycolysis as they enter senescence and sho...